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Western blot analysis of extracts of various cell lines, using PVRL1 antibody (A2037) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
PVRL1 Rabbit pAb
Catalog No：AB-A2037
Manufacturer：ABclonal
Synonyms：NECTIN1;CD111;CLPED1;ED4;HIgR;HV1S;HVEC;OFC7;PRR;PRR1;PVRL1;PVRR;PVRR1;SK-12;nectin-1
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PVRL1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-350 of human PVRL1 (NP_002846.3). |
| Gene ID: | 5818 |
| Swiss prot: | Q15223 |
| Molecular weight: | 39kDa/50kDa/57kDa |
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