PRDM8 Rabbit pAb
Catalog No:AB-A20279
Manufacturer:ABclonal
Synonyms:PFM5; EPM10; KMT8D
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€110,00 – €325,00
Product Name: | PRDM8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PRDM8 (NP_064611.3). |
Gene ID: | 56978 |
Swiss prot: | Q9NQV8 |
Molecular weight: | 71kDa |
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