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Western blot analysis of extracts of various cell lines, using CCR3 antibody (A20253) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded rat spleen using CCR3 Rabbit pAb (A20253) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using CCR3 Rabbit pAb (A20253) at dilution of 1:100 (40x lens).
CCR3 Rabbit pAb
Catalog No：AB-A20253
Manufacturer：ABclonal
Synonyms：CCR3;CC-CKR-3;CD193;CKR3;CMKBR3
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€125,00 – €370,00
| Product Name: | CCR3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. |
| Immunogen: | A synthetic peptide of human CCR3 |
| Gene ID: | 1232 |
| Swiss prot: | P51677 |
| Molecular weight: | 41kDa/43kDa |
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