SARS-CoV-2 N Protein Rabbit mAb
Catalog No:AB-A20021
Manufacturer:ABclonal
Synonyms:Nucleoprotein, NP
Applications:WB,ELISA,FCM,IHC,IF,IP
Reactivity:SARS-CoV-2
Host:Rabbit
Conjugate:No
€195,00 – €2.070,00
Product Name: | SARS-CoV-2 N Protein Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Immunogen: | Recombinant fusion protein of SARS-CoV-2 Nucleoprotein. |
Gene ID: | 1489678 |
Swiss prot: | P59595 |
Molecular weight: |
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