Western blot analysis of extracts from normal (control) and OCRL knockout (KO) 293T cells, using OCRL antibody (A19976) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
[KO Validated] OCRL Rabbit pAb
Catalog No:AB-A19976
Manufacturer:ABclonal
Synonyms:OCRL;INPP5F;LOCR;NPHL2;OCRL-1;OCRL1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | [KO Validated] OCRL Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. |
Immunogen: | Recombinant protein of human OCRL. |
Gene ID: | 4952 |
Swiss prot: | Q01968 |
Molecular weight: | 103kDa/104kDa |
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