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Western blot analysis of extracts from normal (control) and Integrin beta 4 (ITGB4/CD104) knockout (KO) HeLa cells, using Integrin beta 4 (ITGB4/CD104) antibody (A19890) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
[KO Validated] Integrin beta 4 (ITGB4/CD104) Rabbit pAb
Catalog No：AB-A19890
Manufacturer：ABclonal
Synonyms：ITGB4;CD104;GP150
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] Integrin beta 4 (ITGB4/CD104) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen: | Recombinant protein of human Integrin beta 4 (ITGB4/CD104). |
| Gene ID: | 3691 |
| Swiss prot: | P16144 |
| Molecular weight: | 106kDa/194kDa/195kDa/200kDa/202kDa |
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