Western blot analysis of extracts of various cell lines, using Syntrophin alpha 1 Rabbit mAb (A19759) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
Western blot analysis of extracts of Mouse kidney, using Syntrophin alpha 1 Rabbit mAb (A19759) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
Syntrophin alpha 1 Rabbit mAb
Catalog No:AB-A19759
Manufacturer:ABclonal
Synonyms:LQT12, SNT1, TACIP1, dJ1187J4.5
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | Syntrophin alpha 1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) – an inherited disorder associated with sudden cardiac death from arrhythmia – and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013] |
Immunogen: | A synthesized peptide derived from human Syntrophin alpha 1 |
Gene ID: | 6640 |
Swiss prot: | Q13424 |
Molecular weight: | 54kDa |
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