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Western blot analysis of extracts of HeLa cells, using β-Catenin antibody (A19657) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Western blot analysis of extracts of Mouse brain, using β-Catenin antibody (A19657) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Western blot analysis of extracts from normal (control) and β-Catenin knockout (KO) 293T cells, using β-Catenin antibody (A19657) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Immunofluorescence analysis of C6 cells using β-Catenin antibody (A19657) at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded Human cervical squamous cell carcinoma using [KO Validated] β-Catenin Rabbit mAb (A19657) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Human Invasive ductal carcinoma of breast using [KO Validated] β-Catenin Rabbit mAb (A19657) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human lung squamous carcinoma tissue using [KO Validated] β-Catenin Rabbit mAb (A19657) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Human pancreatic ductal carcinoma using [KO Validated] β-Catenin Rabbit mAb (A19657) at dilution of 1:100 (40x lens).
[KO Validated] β-Catenin Rabbit mAb
Catalog No：AB-A19657
Manufacturer：ABclonal
Synonyms：CTNNB;MRD19;armadillo;beta Catenin;CTNNB1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] 尾-Catenin Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
| Immunogen: | A synthesized peptide derived from human beta Catenin. |
| Gene ID: | 1499 |
| Swiss prot: | P35222 |
| Molecular weight: | 92kDa |
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