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Western blot analysis of extracts of various cell lines, using ATM antibody (A19650) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat spleen using ATM antibody (A19650) at dilution of 1:100 (40x lens).
ATM Rabbit mAb
Catalog No：AB-A19650
Manufacturer：ABclonal
Synonyms：AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1;ATM
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | ATM Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] |
| Immunogen: | A synthesized peptide derived from human ATM. |
| Gene ID: | 472 |
| Swiss prot: | Q13315 |
| Molecular weight: | 350kDa |
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