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Western blot analysis of extracts of various cell lines, using Glucocorticoid Receptor antibody (A19583) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
Glucocorticoid Receptor Rabbit mAb
Catalog No：AB-A19583
Manufacturer：ABclonal
Synonyms：GCCR;GCR;GCRST;GR;GRL;NR3C1
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | Glucocorticoid Receptor Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011] |
| Immunogen: | A synthesized peptide derived from human GR. |
| Gene ID: | 2908 |
| Swiss prot: | P04150 |
| Molecular weight: | 95kDa |
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