TIRAP Rabbit pAb
Catalog No:AB-A1943
Manufacturer:ABclonal
Synonyms:TIRAP;BACTS1;Mal;MyD88-2;wyatt
Applications:IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TIRAP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP (NP_001034750.1). |
Gene ID: | 114609 |
Swiss prot: | P58753 |
Molecular weight: | 23kDa/25kDa/27kDa |
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