MyD88 Rabbit pAb
Catalog No:AB-A0980
Manufacturer:ABclonal
Synonyms:MYD88;MYD88D;myeloid differentiation primary response 88;MyD88
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MyD88 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2). |
Gene ID: | 4615 |
Swiss prot: | Q99836 |
Molecular weight: | 15kDa/20kDa/28kDa/31kDa/33kDa/34kDa |
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