Western blot analysis of extracts of SW620 cells, using Caspase-4 antibody (A19305) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5min.
Caspase-4 Rabbit pAb
Catalog No:AB-A19305
Manufacturer:ABclonal
Synonyms:ICE(rel)II;ICEREL-II;ICH-2;Mih1;Mih1/TX;TX;CASP4
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €245,00
Product Name: | Caspase-4 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Immunogen: | Recombinant protein of human Caspase-4. |
Gene ID: | 837 |
Swiss prot: | P49662 |
Molecular weight: |
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