Western blot analysis of extracts of various cell lines, using PRSS2 antibody (A19275) at 1:5000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
PRSS2 Rabbit mAb
Catalog No:AB-A19275
Manufacturer:ABclonal
Synonyms:PRSS2; TRY2; TRY8; TRYP2; trypsin-2
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | PRSS2 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant protein of human PRSS2. |
Gene ID: | 5645 |
Swiss prot: | P07478 |
Molecular weight: | 30kDa |
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