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Western blot analysis of extracts of various cell lines, using ANPRB/NRP2 antibody (A19255) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ANPRB/NRP2 Rabbit mAb
Catalog No：AB-A19255
Manufacturer：ABclonal
Synonyms：NPR2; AMDM; ANPRB; ANPb; ECDM; GUC2B; GUCY2B; NPRB; NPRBi; SNSK; natriuretic peptide receptor 2
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | ANPRB/NRP2 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. |
| Immunogen: | Recombinant protein of human ANPRB/NRP2. |
| Gene ID: | 4882 |
| Swiss prot: | P20594 |
| Molecular weight: | 117kDa |
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