Western blot analysis of extracts of various cell lines, using XPD/ERCC2 antibody (A19241) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
XPD/ERCC2 Rabbit mAb
Catalog No:AB-A19241
Manufacturer:ABclonal
Synonyms:ERCC2; COFS2; EM9; TFIIH; TTD; TTD1; XPD; ERCC excision repair 2, TFIIH core complex helicase subunit
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | XPD/ERCC2 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant protein of human XPD/ERCC2. |
Gene ID: | 2068 |
Swiss prot: | P18074 |
Molecular weight: | 75kDa |
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