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Immunohistochemistry of paraffin-embedded human esophageal cancer using FGFR3 Rabbit mAb (A19052) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of various cell lines, using FGFR3 antibody (A19052) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
FGFR3 Rabbit mAb
Catalog No：AB-A19052
Manufacturer：ABclonal
Synonyms：ACH;CD333;CEK2;HSFGFR3EX;JTK4;FGFR3
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | FGFR3 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009] |
| Immunogen: | A synthesized peptide derived from human FGFR3 |
| Gene ID: | 2261 |
| Swiss prot: | P22607 |
| Molecular weight: | 98kDa |
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