Western blot analysis of extracts of various cell lines, using NTRK1/NTRK2/NTRK3 antibody (A18809) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
NTRK1/NTRK2/NTRK3 Rabbit pAb
Catalog No:AB-A18809
Manufacturer:ABclonal
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NTRK1/NTRK2/NTRK3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer. |
Immunogen: | Recombinant protein of human NTRK1/NTRK2/NTRK3. |
Gene ID: | 4914/4915/4916 |
Swiss prot: | P04629/Q16620/Q16288 |
Molecular weight: |
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