KDM2A Rabbit pAb
Catalog No:AB-A18636
Manufacturer:ABclonal
Synonyms:KDM2A; CXXC8; FBL11; FBL7; FBXL11; JHDM1A; LILINA; lysine demethylase 2A
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KDM2A Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant protein of human KDM2A. |
Gene ID: | 22992 |
Swiss prot: | Q9Y2K7 |
Molecular weight: | 69kDa/81kDa/89kDa/96kDa/132kDa |
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