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Western blot analysis of extracts of various cell lines, using NBS1/NBS1/NBN antibody (A0783) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Western blot analysis of extracts from normal (control) and NBS1/NBS1/NBN knockout (KO) 293T cells, using NBS1/NBS1/NBN antibody (A0783) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human lung cancer using [KO Validated] NBS1/NBS1/NBN Rabbit pAb (A0783) at dilution of 1:50 (40x lens).
[KO Validated] NBS1/NBN Rabbit pAb
Catalog No：AB-A0783
Manufacturer：ABclonal
Synonyms：NBN;AT-V1;AT-V2;ATV;NBS;NBS1;P95;nibrin
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] NBS1/NBN Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBS1/NBS1/NBN (NP_002476.2). |
| Gene ID: | 4683 |
| Swiss prot: | O60934 |
| Molecular weight: | 84kDa |
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