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Western blot analysis of extracts of various cell lines, using PSAP antibody (A1819) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
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Immunohistochemistry of paraffin-embedded human breast cancer using PSAP Rabbit pAb (A1819) at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded human placenta using PSAP Rabbit pAb (A1819) at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using PSAP Rabbit pAb (A1819) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat kidney using PSAP Rabbit pAb (A1819) at dilution of 1:100 (40x lens).
PSAP Rabbit pAb
Catalog No：AB-A1819
Manufacturer：ABclonal
Synonyms：PSAP;GLBA;SAP1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PSAP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human PSAP (NP_002769.1). |
| Gene ID: | 5660 |
| Swiss prot: | P07602 |
| Molecular weight: | 58kDa |
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