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Western blot analysis of extracts from normal (control) and TMED10 knockout (KO) 293T cells, using TMED10 antibody (A18090) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
[KO Validated] TMED10 Rabbit pAb
Catalog No：AB-A18090
Manufacturer：ABclonal
Synonyms：TMED10;P24(DELTA);S31I125;S31III125;TMP21;Tmp-21-I;p23;p24d1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] TMED10 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex’s gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer’s disease. This gene has a pseudogene on chromosome 8. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3). |
| Gene ID: | 10972 |
| Swiss prot: | P49755 |
| Molecular weight: | 24kDa |
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