Western blot analysis of extracts of HeLa cells, using GRB10 antibody (A0634) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
GRB10 Rabbit pAb
Catalog No:AB-A0634
Manufacturer:ABclonal
Synonyms:GRB10;GRB-IR;Grb-10;IRBP;MEG1;RSS
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GRB10 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRB10 (NP_005302.3). |
Gene ID: | 2887 |
Swiss prot: | Q13322 |
Molecular weight: | 60kDa/62kDa/66kDa/67kDa |
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