Western blot analysis of extracts of various cell lines, using AGRN antibody (A17320) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
AGRN Rabbit pAb
Catalog No:AB-A17320
Manufacturer:ABclonal
Synonyms:AGRN;AGRIN;CMS8;CMSPPD;agrin
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | AGRN Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-350 of human AGRN (NP_940978.2). |
Gene ID: | 375790 |
Swiss prot: | O00468 |
Molecular weight: | 217kDa |
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