TLR5 Rabbit pAb
Catalog No:AB-A1721
Manufacturer:ABclonal
Synonyms:MELIOS;SLE1;SLEB1;TIL3;TLR5
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TLR5 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 714-858 of human TLR5 (NP_003259.2). |
Gene ID: | 7100 |
Swiss prot: | O60602 |
Molecular weight: | 97kDa |
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