Western blot analysis of extracts of various cell lines, using KAT6B antibody (A17116) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
KAT6B Rabbit pAb
Catalog No:AB-A17116
Manufacturer:ABclonal
Synonyms:KAT6B;GTPTS;MORF;MOZ2;MYST4;ZC2HC6B;qkf;querkopf
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KAT6B Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1). |
Gene ID: | 23522 |
Swiss prot: | Q8WYB5 |
Molecular weight: |
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