Western blot analysis of extracts of various cell lines, using LRRFIP2 Rabbit pAb (A17046) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
LRRFIP2 Rabbit pAb
Catalog No:AB-A17046
Manufacturer:ABclonal
Synonyms:LRRFIP2;HUFI-2
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LRRFIP2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-340 of human LRRFIP2 (NP_060194.1). |
Gene ID: | 9209 |
Swiss prot: | Q9Y608 |
Molecular weight: |
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