Western blot analysis of extracts of various cell lines, using NAIP antibody (A16924) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
NAIP Rabbit pAb
Catalog No:AB-A16924
Manufacturer:ABclonal
Synonyms:NAIP;BIRC1;NLRB1;psiNAIP
Applications:WB
Reactivity:Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NAIP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 750-850 of human NAIP (NP_075043.1). |
Gene ID: | 4671 |
Swiss prot: | Q13075 |
Molecular weight: |
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