Western blot analysis of extracts of various cell lines, using GFI1 Rabbit pAb (A16862) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
GFI1 Rabbit pAb
Catalog No:AB-A16862
Manufacturer:ABclonal
Synonyms:GFI1;GFI-1;GFI1A;SCN2;ZNF163
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GFI1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GFI1 (NP_001120687.1). |
Gene ID: | 2672 |
Swiss prot: | Q99684 |
Molecular weight: | 45kDa |
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