Western blot analysis of extracts of various cell lines, using CHRNA3 antibody (A1674) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
CHRNA3 Rabbit pAb
Catalog No:AB-A1674
Manufacturer:ABclonal
Synonyms:CHRNA3;LNCR2;NACHRA3;PAOD2
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CHRNA3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human CHRNA3 (NP_000734.2). |
Gene ID: | 1136 |
Swiss prot: | P32297 |
Molecular weight: | 55kDa/57kDa |
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