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Western blot analysis of extracts of various cell lines, using FGD1 antibody (A16709) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
FGD1 Rabbit pAb
Catalog No：AB-A16709
Manufacturer：ABclonal
Synonyms：FGD1;AAS;FGDY;MRXS16;ZFYVE3;FYVE
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | FGD1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2). |
| Gene ID: | 2245 |
| Swiss prot: | P98174 |
| Molecular weight: | 106kDa |
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