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Western blot analysis of extracts of Rat pancreas, using FBN1 antibody (A16677) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
FBN1 Rabbit pAb
Catalog No：AB-A16677
Manufacturer：ABclonal
Synonyms：FBN1;ACMICD;ECTOL1;FBN;GPHYSD2;MASS;MFLS;MFS1;OCTD;SGS;SSKS;WMS;WMS2
Applications：WB,IF
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | FBN1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-460 of human FBN1 (NP_000129.3). |
| Gene ID: | 2200 |
| Swiss prot: | P35555 |
| Molecular weight: | 312kDa |
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