Western blot analysis of extracts of various cell lines, using OPTC antibody (A16514) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
OPTC Rabbit pAb
Catalog No:AB-A16514
Manufacturer:ABclonal
Synonyms:OPTC;OPT;opticin
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | OPTC Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-115 of human OPTC (NP_055174.1). |
Gene ID: | 26254 |
Swiss prot: | Q9UBM4 |
Molecular weight: | 37kDa |
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