Western blot analysis of extracts of various cell lines, using CD11a/LFA-1A/ITGAL antibody (A1644) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
CD11a/LFA-1A/ITGAL Rabbit pAb
Catalog No:AB-A1644
Manufacturer:ABclonal
Synonyms:CD11A;LFA-1;LFA1A;CD11a;ITGAL
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CD11a/LFA-1A/ITGAL Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD11a/LFA-1A/ITGAL (NP_001107852.1). |
Gene ID: | 3683 |
Swiss prot: | P20701 |
Molecular weight: | 119kDa/128kDa/134kDa |
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