PITX2 Rabbit pAb
Catalog No：AB-A16417
Manufacturer：ABclonal
Synonyms：PITX2;ARP1;ASGD4;Brx1;IDG2;IGDS;IGDS2;IHG2;IRID2;Otlx2;PTX2;RGS;RIEG;RIEG1;RS
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | PITX2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human PITX2 (NP_000316.2). |
| Gene ID: | 5308 |
| Swiss prot: | Q99697 |
| Molecular weight: | 30kDa/35kDa |
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