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Immunohistochemistry of paraffin-embedded human placenta using Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) antibody (A16336) at dilution of 1:100 (40x lens).
Alpha-2-Macroglobulin (A2M) Rabbit pAb
Catalog No：AB-A16336
Manufacturer：ABclonal
Synonyms：A2M;A2MD;CPAMD5;FWP007;S863-7
Applications：WB,IHC
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Alpha-2-Macroglobulin (A2M) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) (NP_000005.2). |
| Gene ID: | 2 |
| Swiss prot: | P01023 |
| Molecular weight: | 163kDa |
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