Western blot analysis of extracts of various cell lines, using ESRα (ESR1) antibody (A0296) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
ESRα Rabbit pAb
Catalog No:AB-A0296
Manufacturer:ABclonal
Synonyms:ESR1;ER;ESR;ESRA;ESTRR;Era;NR3A1;ER alpha
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ESRα Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ESRα (ESR1) (NP_000116.2). |
Gene ID: | 2099 |
Swiss prot: | P03372 |
Molecular weight: | 35kDa/47kDa/53kDa/66kDa |
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