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Western blot analysis of extracts of various cell lines, using APP antibody (A16265) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Western blot analysis of extracts of 293T cells, using APP antibody (A16265) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat brain using APP antibody (A16265) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human colon using APP antibody (A16265) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human colon carcinoma using APP antibody (A16265) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse cerebellum using APP antibody (A16265) at dilution of 1:200 (40x lens).
APP Rabbit pAb
Catalog No：AB-A16265
Manufacturer：ABclonal
Synonyms：AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;Amyloid beta A4;APP;Aβ42;preA4
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | APP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Immunogen: | A synthetic peptide of human Aβ42. |
| Gene ID: | 351 |
| Swiss prot: | P05067 |
| Molecular weight: | 34kDa/72-86kDa |
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