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Western blot analysis of extracts of various cell lines, using SDHD antibody (A16240) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
SDHD Rabbit pAb
Catalog No：AB-A16240
Manufacturer：ABclonal
Synonyms：SDHD;CBT1;CII-4;CWS3;PGL;PGL1;QPs3;SDH4;cybS
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SDHD Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SDHD (NP_002993.1). |
| Gene ID: | 6392 |
| Swiss prot: | O14521 |
| Molecular weight: | 9kDa/12kDa/15kDa/17kDa |
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