Western blot analysis of extracts of various cell lines, using CEP290 antibody (A16147) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
CEP290 Rabbit pAb
Catalog No:AB-A16147
Manufacturer:ABclonal
Synonyms:CEP290;3H11Ag;BBS14;CT87;JBTS5;LCA10;MKS4;NPHP6;POC3;SLSN6;rd16
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CEP290 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1050 of human CEP290 (NP_079390.3). |
Gene ID: | 80184 |
Swiss prot: | O15078 |
Molecular weight: | 180kDa/290kDa |
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