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Western blot analysis of extracts of various cell lines, using TAP2 antibody (A1610) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded human colon carcinoma using TAP2 Rabbit pAb (A1610) at dilution of 1:100 (40x lens).
TAP2 Rabbit pAb
Catalog No：AB-A1610
Manufacturer：ABclonal
Synonyms：TAP2;ABC18;ABCB3;APT2;D6S217E;PSF-2;PSF2;RING11
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TAP2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-680 of human TAP2 (NP_000535.3). |
| Gene ID: | 6891 |
| Swiss prot: | Q03519 |
| Molecular weight: | 72kDa/75kDa |
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