Western blot analysis of extracts of 293T cells, using ANPRB/NRP2 antibody (A16061) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
ANPRB/NRP2 Rabbit pAb
Catalog No:AB-A16061
Manufacturer:ABclonal
Synonyms:NPR2;AMDM;ANPRB;ANPb;ECDM;GUC2B;GUCY2B;NPRB;NPRBi;SNSK
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ANPRB/NRP2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-320 of human ANPRB/NRP2 (NP_003986.2). |
Gene ID: | 4882 |
Swiss prot: | P20594 |
Molecular weight: | 111kDa/117kDa |
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