ERCC5 Rabbit pAb
Catalog No:AB-A1605
Manufacturer:ABclonal
Synonyms:ERCC5;COFS3;ERCC5-201;ERCM2;UVDR;XPG;XPGC
Applications:IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ERCC5 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a single-strand specific DNA endonuclease that makes the 3′ incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ERCC5 (NP_000114.2). |
Gene ID: | 2073 |
Swiss prot: | P28715 |
Molecular weight: | 27kDa/47kDa/133kDa |
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