Western blot analysis of extracts of various cell lines, using NLRP10 antibody (A15976) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
NLRP10 Rabbit pAb
Catalog No:AB-A15976
Manufacturer:ABclonal
Synonyms:NLRP10;CLR11.1;NALP10;NOD8;PAN5;PYNOD
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | NLRP10 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NLRP10 (NP_789791.1). |
Gene ID: | 338322 |
Swiss prot: | Q86W26 |
Molecular weight: | 75kDa |
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