MLH1 Rabbit pAb
Catalog No:AB-A0254
Manufacturer:ABclonal
Synonyms:MLH1;COCA2;FCC2;HNPCC;HNPCC2;hMLH1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MLH1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-600 of human MLH1 (NP_000240.1). |
Gene ID: | 4292 |
Swiss prot: | P40692 |
Molecular weight: | 58kDa/73kDa/84kDa |
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