Western blot analysis of extracts of various cell lines, using MYOC antibody (A1589) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
MYOC Rabbit pAb
Catalog No:AB-A1589
Manufacturer:ABclonal
Synonyms:MYOC;GLC1A;GPOA;JOAG;JOAG1;TIGR;myocilin
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MYOC Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_000252.1). |
Gene ID: | 4653 |
Swiss prot: | Q99972 |
Molecular weight: | 56kDa |
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