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Western blot analysis of extracts of various cell lines, using Renin antibody (A1585) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Renin Rabbit pAb
Catalog No：AB-A1585
Manufacturer：ABclonal
Synonyms：REN;HNFJ2;renin;Renin
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Renin Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Renin catalyzes the first step in the activation pathway of angiotensinogen–a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human Renin (NP_000528.1). |
| Gene ID: | 5972 |
| Swiss prot: | P00797 |
| Molecular weight: | 44kDa/45kDa |
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