Western blot analysis of extracts of rat pancreas, using ASCC1 antibody (A15832) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
ASCC1 Rabbit pAb
Catalog No:AB-A15832
Manufacturer:ABclonal
Synonyms:ASCC1;ASC1p50;CGI-18;SMABF2;p50
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ASCC1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_001185727.1). |
Gene ID: | 51008 |
Swiss prot: | Q8N9N2 |
Molecular weight: | 41kDa/45kDa |
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