Western blot analysis of extracts of Mouse liver, using IL6R antibody (A1570) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
IL6R Rabbit pAb
Catalog No:AB-A1570
Manufacturer:ABclonal
Synonyms:IL6R;CD126;IL-6R-1;IL-6RA;IL6Q;IL6RA;IL6RQ;gp80
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IL6R Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL6R (NP_000556.1). |
Gene ID: | 3570 |
Swiss prot: | P08887 |
Molecular weight: | 40kDa/51kDa |
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