Western blot analysis of extracts of various cell lines, using GITR/TNFRSF18 antibody (A15625) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
GITR/TNFRSF18 Rabbit pAb
Catalog No:AB-A15625
Manufacturer:ABclonal
Synonyms:TNFRSF18;AITR;CD357;GITR;GITR-D
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GITR/TNFRSF18 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-255 of human GITR/TNFRSF18 (NP_683699.1). |
Gene ID: | 8784 |
Swiss prot: | Q9Y5U5 |
Molecular weight: | 25kDa/26kDa |
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